Napoli fell to a 2-1 defeat, with defender Giovanni di Lorenzo being sent off in the first half.
Hojlund acknowledged the challenge of playing against Manchester City, especially when facing 11 players against 10.
He stated that playing at Manchester City's stadium is already difficult, but losing a player to a red card makes it even more challenging.
Hojlund also spoke about the substitution of former Manchester City star Kevin de Bruyne, saying that he wanted to play, but the coach made the decision and it was respected.
However, Hojlund praised de Bruyne, noting his quality and skills as a player.